Which deficiency diseases is caused lack of vitamin E ?

Deficiency and toxicity of vitamin E

Vitamin E;

Vitamin E (active from: alpha -tocopherol) is a fat- soluble vitamin with antioxidant properties . It is the one of the body 's primary defenses against the adverse affect of free radicals, thus protecting the biomolecules and cell membranes from destruction.

It also play role in preventing the oxidation of poly-unsaturated fatty acid (PUFA). Moreover, it can reduce the risk of the heart diseases by protecting oxidation of low-density lipoprotein(LDL).the RDA of vitamin E for adults in15mg per day.

Vitamin E deficiency:

The primary deficiency linked with inadequate intake of vitamin E is rare; whoever, other diseases like cystic, fibrosis, attributed to fat malabsorption can lead to vitamin E deficiency.

The common consequence of vitamin E deficiency is erythrocyte hemolysis, which leads to hemolytic anemia(having too few red blood cells)lack of vitamin E can cause oxidation of PUFA in their membranes that result in the breakage of red blood cells (open and spill their contents).

Persistent deficiency of vitamin E cause neuromuscular dysfunctions involving spinal cord and retina of the eye. The loss of muscle coordination, reflexes, and impaired vision are other symptoms of vitamin E deficiency.

Causes:

Vitamin E deficiency is usually caused by a condition that reduces the absorption of dietary fats. These conditions include:

Diseases of the pancreas, liver, or gallbladder

Genetic disorders such as abetalipoproteinemia or familial isolated vitamin E deficiency

Premature, very low birth weight infants (birth weights less than 1500 grams, or 3.5 pounds)

Symptoms:

The primary symptoms of vitamin E deficiency relate to nerve and muscle damage. Symptoms can include:

Treatment:

Treatment for vitamin E deficiency typically involves vitamin E supplements under the care of a doctor. The underlying cause of the deficiency also needs to be addressed.

Vitamin E Toxicity:

While vitamin E is considered safe for most people when taken in recommended amounts, high doses can cause serious side effects.

Vitamin E toxicity: Increased supplemental use of vitamin E results in toxicity that is uncommon.

Toxic amount of vitamin E may interfere with vitamin K functioning, thereby hindering the blood clotting action of vitamin K by increasing the effect of drugs, resulting in hemorrhage(a condition characterized by the excessive bleeding). Other symptoms of vitamins E toxicity are listed below:

1) Digestion symptoms: Nausea, stomach cramps.

2) Eye symptoms: Blurred vision.

3) Muscular symptoms: Fatigue

Causes:

The primary cause of vitamin E toxicity is overconsumption of vitamin E supplements. Vitamin E is fat-soluble, which means excess amounts are stored in the body rather than excreted.

Symptoms:

Taking high doses of vitamin E might increase the risk of certain side effects. These may include:

Nausea
Diarrhea
Stomach cramps
Fatigue
Weakness
Headache
Blurred vision
Rash
Bruising and bleeding

Over time, high levels of vitamin E might also increase the risk of hemorrhagic stroke and prostate cancer.

Source of vitamin E ;

Nuts and seeds: Almonds, peanuts, hazelnuts, and sunflower seeds are among the best sources of vitamin E.

Green leafy vegetables: Spinach and broccoli are good sources.

Vegetable oils: Wheat germ oil, sunflower oil, safflower oil, and corn oil are high in vitamin E.

Fruits: Kiwi and mango provide some vitamin E.

Seafood: Shellfish and fish like salmon and rainbow trout are decent sources of vitamin E.

Fortified cereals and juice: Many breakfast cereals and fruit juices are fortified with vitamin E.

Whole grains: Whole grain products can provide some vitamin E.

Eggs and meat: Some types of meat like goose meat and eggs are decent sources of vitamin E.

Remember, eating a balanced diet is the best way to get the necessary amounts of all vitamins, including vitamin E. Also, individual requirements may vary, so it's important to consult with a healthcare provider or a nutritionist for personalized advice