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Friday, August 4, 2023

How is Plasmodium vivax transmitted to humans?

 Type of Malaria?

Plasmodium vivax is a protozoan parasite that causes malaria in humans. It is one of the five species of the Plasmodium parasite that can cause malaria in humans, the others being Plasmodium falciparum, Plasmodium malaria, Plasmodium ovale, and Plasmodium Knowles.



Symptom:

The symptoms of Plasmodium vivax infection can vary from person to person, but some of the most common symptoms include:

  1. Fever
  2. Chills
  3. Sweating
  4. Headache
  5. Muscle pain
  6. Fatigue
  7. Nausea and vomiting
  8. Diarrhea
  9. Enlarged spleen
  10. Anemia
  11. Jaundice (yellowing of the skin and eyes)
  12. Dark urine
  13. Abdominal pain

It's worth noting that some people may not show any symptoms of Plasmodium vivax infection, especially if they have developed immunity to the parasite over time. However, if left untreated, malaria caused by Plasmodium vivax can lead to more severe symptoms, such as seizures, coma, and even death. Therefore, it's important to seek medical attention if you suspect that you have been infected with Plasmodium vivax or any other type of malaria parasite.


Cause:

Mosquito bites: Plasmodium vivax is transmitted to humans through the bites of infected female Anopheles mosquitoes.

Presence of infected people: The spread of Plasmodium vivax is facilitated by the presence of infected people who can act as carriers of the parasite. If a mosquito bites an infected person, it can become infected and transmit the parasite to other people.

Poor living conditions: Plasmodium vivax is more common in areas with poor living conditions such as inadequate sanitation, poor housing, and limited access to healthcare.

Climate: Plasmodium vivax is more prevalent in areas with warm and humid climates, as these conditions are favorable for the growth and survival of the Anopheles mosquito.

Lack of preventive measures: The use of mosquito nets, insect repellents, and other preventive measures can help reduce the spread of Plasmodium vivax. However, in areas where these measures are not widely used, the risk of infection is higher.

Prevention of Plasmodium vivax:

Plasmodium vivax is a type of parasite that causes malaria. The prevention of Plasmodium vivax primarily involves measures to avoid mosquito bites and to reduce the mosquito population.

Use mosquito nets: Sleeping under a mosquito net is one of the most effective ways to prevent malaria. Mosquito nets can be treated with insecticide, which kills mosquitoes that come into contact with the net.

Wear protective clothing: Wearing long-sleeved shirts and long pants can help reduce the amount of skin exposed to mosquito bites. It is also advisable to wear light-colored clothing as mosquitoes are attracted to darker colors.

Use insect repellent: Insect repellents containing DEET (N, N-diethyl-meta-toluamide) or Picaridin can be applied to the skin to deter mosquitoes from biting. Repellents should be used as per the instructions on the label.

Eliminate mosquito breeding sites: Mosquitoes breed in stagnant water, so it is important to eliminate any standing water around your home. This can be achieved by emptying or covering outdoor containers that hold water, such as buckets, flowerpots, and old tires.

Take antimalarial medication: Taking antimalarial medication as prescribed by a doctor can help prevent malaria. The type of medication prescribed depends on the type of malaria parasite present in the area, as well as any other factors that may affect the individual's health.

Avoid outdoor activities at dusk and dawn: Mosquitoes are most active during these times, so it is advisable to stay indoors or take extra precautions to avoid mosquito bites during these hours.

Seek medical attention promptly: If you develop symptoms of malaria such as fever, chills, headache, and muscle aches, seek medical attention immediately. Early diagnosis and treatment can help prevent serious complications of the disease.

Here are some general guidelines on what to eat and avoid if you have or are at risk of Plasmodium vivax malaria:

What to eat:

  • A balanced and nutritious diet can help support your immune system and improve your overall health.
  • Foods rich in iron, such as leafy greens, red meat, poultry, fish, beans, and fortified cereals, can help combat the anemia that can occur with malaria infection.
  • Vitamin C-rich foods, such as citrus fruits, kiwis, and bell peppers, can help boost your immune system and support the absorption of iron.
  • Drinking plenty of fluids, such as water, coconut water, and herbal tea, can help prevent dehydration, which is a common complication of malaria.

What to avoid:

  • Alcohol and caffeine can dehydrate you and worsen the symptoms of malaria, so it's best to avoid or limit your intake of these beverages.
  • Sugary and processed foods can weaken your immune system and cause inflammation, so it's best to limit your intake of these foods and focus on whole, unprocessed foods instead.
  • Raw or undercooked meat, fish, or eggs can increase your risk of other foodborne illnesses, so it's best to cook these foods thoroughly before eating them.
It's important to note that these dietary recommendations are general and may vary depending on your individual health needs and the severity of your malaria infection. If you have malaria, it's best to follow your doctor's advice and treatment plan, which may include additional dietary recommendations.

Diagnosis of Plasmodium vivax 

Plasmodium vivax is a type of parasite that causes malaria in humans. The diagnosis of P. vivax infection is usually made by detecting the presence of the parasite in blood samples using various diagnostic tests.

Some of the commonly used diagnostic tests for P. vivax include:

Microscopic examination of blood smears: A blood smear is prepared by placing a drop of blood on a glass slide, staining it with special stains, and examining it under a microscope. The presence of P. vivax parasites can be detected by observing the characteristic morphology of the parasite in the blood sample.

Rapid diagnostic tests (RDTs): RDTs are simple, easy-to-use diagnostic tests that can detect the presence of P. vivax antigens in blood samples. They work by using specific antibodies that bind to P. vivax antigens and produce a visible result.

Polymerase chain reaction (PCR): PCR is a highly sensitive technique that can detect even very low levels of P. vivax DNA in blood samples. It involves amplifying specific regions of the parasite DNA using specific primers and detecting the amplified product using specialized equipment.

Serological tests: Serological tests can detect antibodies to P. vivax in blood samples. However, these tests are not useful for diagnosing acute infections, as it takes several weeks for the antibodies to develop.

The choice of diagnostic test depends on various factors, including the availability of resources, the expertise of the personnel, and the stage of the infection. It is important to diagnose and treat P. vivax infection promptly to prevent severe complications and spread of the disease.

Treatment:

Treatment for this disease typically involves the use of antimalarial medications to kill the parasites and relieve symptoms. Here are the key points for the treatment of Plasmodium vivax:

Diagnosis: A confirmed diagnosis of P. vivax malaria is made by blood tests such as a blood smear or rapid diagnostic test.

Antimalarial medications: The main medications used to treat P. vivax are chloroquine and primaquine.

Chloroquine: This medication is used to kill the asexual stage of the parasite. The usual dose is 25mg/kg over 3 days. In some areas where chloroquine resistance is high, other medications such as artemether-lumefantrine or quinine may be used instead.

Primaquine: This medication is used to kill the hypnozoite stage of the parasite that can cause relapses. The usual dose is 0.25mg/kg/day for 14 days. Primaquine can cause hemolysis in people with G6PD deficiency.

Supportive care: Symptomatic treatment includes rest, rehydration, and fever-reducing medications such as paracetamol.

Monitoring: Regular blood tests are necessary to monitor the effectiveness of treatment and check for complications such as anemia or kidney dysfunction.

Prevention: Malaria prevention measures include the use of insect repellent, mosquito nets, and antimalarial medications when traveling to areas where P. vivax is common.

It's important to follow the treatment regimen as directed by a healthcare provider and to complete the full course of medications to ensure complete elimination of the parasite.


  1. 1. What is Plasmodium vivax and how does it relate to malaria?
  2. 2. How is Plasmodium vivax transmitted to humans?
  3. 3. What are the distinctive features of the life cycle of Plasmodium vivax?
  4. 4. How does Plasmodium vivax cause symptoms in an infected individual?
  5. 5. What are the diagnostic methods and treatment options for Plasmodium vivax infections?
  6. What is the common name for Plasmodium vivax?
  7. How is Plasmodium vivax transmitted?

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